6. Dopamine & Glutamate in Addiction
February 6, 2010 - 11:06 pm
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Meta
February 6th, 2010 at 11:39 pm
I’m curious…do you mean using isn’t always a bad thing or are you actually saying that true addiction can be anything but less than pleasant?
February 7th, 2010 at 12:29 am
yes.
February 7th, 2010 at 12:45 am
so, you’re actually suggesting that addiction doesn’t always suck?
really?
February 7th, 2010 at 1:34 am
I’m not sure that’s quite true, weed. The cannabinoid system is separate, that’s true, but so is the opioid system .. and opioids are definitely addictive. The CN system, when stimulated, does cause an increase in extracellular dopamine in the reward structures of the midbrain. And no, I’m not a tool of the government … (at least I don’t think so)
February 7th, 2010 at 1:51 am
What lies? He’s explaining how many drugs work. This isn’t propaganda, dumbass.
February 7th, 2010 at 2:05 am
because marijuana dosent work on Dopamine . all it does is stimulate canabanoid receptors in your brain witch are located in a bunch of differnt areas in your brain
February 7th, 2010 at 3:02 am
pharmacological duct tape?
February 7th, 2010 at 3:52 am
what if your hose has a hole in it?
February 7th, 2010 at 3:58 am
i dont know if this video was specifically referring to marijuana. Some drugs are much are addicting than other and are much more able to change the chemistry of your brain. I dont think marijuana is one of those drugs
February 7th, 2010 at 4:00 am
seriously man? you act like a tool of the government, throwing fear into our brains with these lies. man, addiction can suck but it doesnt always.
February 7th, 2010 at 4:32 am
now im personally curious, how is it that some marijuana studies show it helping the brain? i dont know if the thc affects things differently than shown here, but i have verry little experience studying anything in the brain. i could have misunderstood the study also
February 7th, 2010 at 5:19 am
methadone kills…nicotine replacement therapy is one thing…heroin replacement therapy is stupid. Oh, the withdrawals from heroin are uncomfortable you say? The argument of an addict. Alcoholics die from withdrawal, heroin addicts do not. Let’s propogate their addiction with a prescription to get high….just plain stupid. I am not a “normie”, im speaking from a place of experience in addiction.
February 7th, 2010 at 5:56 am
Hi Sav! Thanks very much … believe me, I’m working as hard as I can to make our program affordable to everyone. Good luck to you!
KTM
February 7th, 2010 at 6:07 am
It seems as if you have a fine establishment there. it is too bad I can’t afford it, my 200 dollar day heroin habit keeps me strapped for cash! Just kidding of coarse, my habit is now an hour trip to a methadone clinic which also keeps me strapped for cash. Unfortunately, it is all I have at the moment. Good new is: I haven’t cheated myself in over two years and I’ve went from 90mgs to 30mgs and counting. but seriously, fine program!
February 7th, 2010 at 6:34 am
… as for opioid receptors, not only are they down-regulated when exogenous opioids (like heroin) are used, but the receptors are “trafficked” in that, once bound, they are absorbed into the cell, altered, and then represented to the surface … lots of changes even from drug use episode to episode
February 7th, 2010 at 7:04 am
Hi Ego! … I think a full pleasurable experience has a little bit of all of these neurotransmitters. I like to think of the “yum!” of chocolate cake, for instance, as a bit like a tree sawed in half – the innermost ring is dopamine, the next outer rings are serotonin and norepi, then the real consummatory pleasure – the “Yum” we typically associate with something feeling good – involves the outermost rings: the opioid and cannabinoid systems and maybe even neurohormones like oxytocin.
February 7th, 2010 at 7:52 am
dopamine is the neurotransmitter used by meth, cocaine and other stimulants. but what about the opiate receptors? is there a similar give and take that is erased by too many “floods”?